Tag Archives: MIT

Detecting patients’ pain levels via their brain signals | MIT News

Researchers from MIT and elsewhere have developed a system that measures a patient’s pain level by analyzing brain activity from a portable neuroimaging device. The system could help doctors diagnose and treat pain in unconscious and noncommunicative patients, which could … Continue reading

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OPTOGENETICS: the science of CONTROLLING GENES (HUMAN GENETICS) via LIGHT. Including ANGER, EMOTIONS and BRAIN FUNCTION video lectures…

optogenetics, which uses proteins that change their function in response to light can rapidly start or halt the expression of any gene of interest simply by shining light on the cells.
Optogenetics is a technique that allows scientists to control neurons’ electrical activity with light by engineering them to express light-sensitive proteins.
The red-light-sensitive opsin, which the researchers named Chrimson, can mediate neural activity in response to light with a 735-nanometer wavelength.
Working to modify Chrimson to respond to light in the infrared range.
Also working on making both Chrimson and Chronos faster and more light sensitive.

relation between anger, the amygdala and the prefrontal cortex

major scientific discoveries on “split-brain” functioning and the duality of consciousness.
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Viral vectors are a key technology for neuroscience research, allowing delivery of genes into the brain to manipulate brain function- viruses can be delivered with spatial and temporal specificity, and can be engineered to produce cell-type specificity of expression. Importantly, viruses can also be used for genetic manipulation of species

Viral vectors are a key technology for neuroscience research, allowing delivery of genes into the brain to manipulate brain function.

In addition to their speed and cost advantages, viruses can be delivered with spatial and temporal specificity, and in some cases can be engineered to produce cell-type specificity of expression.

The viral gene transfer core was established in 2008 by the Picower Institute and the McGovern Institute to make viral vectors accessible to the MIT neuroscience community.
Directed by Rachael Neve, its overall goals are to provide the most advanced viral vector technologies, and to drive the development of new applications that will benefit neuroscience research.

The production of viruses requires special expertise, and given the range of vectors now available, it is not easy for individual labs to develop the necessary expertise to take full advantage of these technologies. Continue reading

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